Application and effects of xanthohumol

Anti-inflammatory

Inflammation, particularly in its chronic form, is at the root of many modern civilization diseases. 
Of course, inflammation can be caused by different factors, but the consequences and the mechanism of inflammation itself are very similar. It is important to know where in the body the inflammation occurs, e.g. in the intestines, liver or skin, as this determines the disease entity we are dealing with.
Xanthohumol demonstrates exceptionally strong anti-inflammatory properties, often showing noticeable effects after just 2-3 doses.
Xanthohumol owes its properties to its effects on inflammatory pathways through inhibition of the farsenoid X receptor (FXR) and NF-kB which inhibits the pro-inflammatory gene expressions of Interleukin IL-1B, IL-6, IL-8, IL-12, and Tumour necrosis factor (TNF). This action is important both in the context of the so-called cytokine storm in Covid’s infections as well as in other inflammatory reactions. 
Xanthohumol extinguishes these conditions by having a significant effect on reducing the production of nitric oxide (NO), which plays an important role in inflammatory processes and tumour formation.

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